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KeithShuttLeworth&.AssociatesLimitedSQ2SANITARYSAMPLECOOLERMANUAL_(THISMANUALCONTAINSBOTHMATERIALANDCOMPONENTCERTIFICATIONANDSHOULDBESECURELYSTORED)JOBNUMBER8781KEITHSHUTTLEWORTH&ASSOCIATESLIMITED5DBasepointBusinessCentre,110Butterfield,Luton,LU29DLUnitedKingdomPhone+44(0)1582433723Fax+44(0)207117:1251E-mailksa@ksapharma.comKeithShuttleworthftAssociatesLimitedINDEX1.General2.Installation3.Operation4.Sterilization5.Maintenance6.Certification-Wettedparts~v..',I...;\...".eN.'~G,KeithShuttleworth&AssociatesLimited1.0GENERALThismanualproVidesallofthenecessaryinstallation,operatingandsafetyinstructionsandmustbereadbeforetheSQ2SanitarySampleCoolerisputintoservice.TheSQ2SanitarySampleCoolerisspecificallydesignedtoallowcleansteamandwaterforInjection(WFI)samplestobetakensafely,quicklyandeasilywhilstminimisingtheriskofcontaminationduringsampling.SteamlWFIentersthesamplecoolerbymeansofasanitaryconnectionatthetopofthecoolerandiscondensed/cooledbyacounterflowofacoolingmedium,typicallymainsortankcoldwater,whichflowsfromthebottomofthecoolertothetop.TheSQ2SanitarySampleCoolerutilisesahighqualitysurfacefinishstainlesssteelcoolingcoiltominimisecorrosionandconsequentcontaminationofthesamplefromthesamplingdevice.SPECIFICATIONSampleconnectionsW'Tri-Clamp©compatibleCoolingwaterconnectionsCoilsurfacearea1/2"BSP/NPT0.113rn2(1.217ff)Coildesignpressure115barg(215psig)/198°C(388°F)Shelldesignpressure110barg(145psig)/1000C(212°F)Weight2.0kg(4.4Ibs)Capacities(approximate)*Steam160ml/minute*Water500ml/minute*Assumescoolingwaterat200Candflow@6litres/minute(95USgallons/hour)1Pressure/temperatureratingisalsodependentuponTri-Clamp©&sealsuppliersspecification.TheSQ2SanitarySampleCoolermustnotbeusedoutsidetheparametersdetailedabove.TheSQ2SanitarySampleCoolerisexemptfromCEmarkingasPED97/23/ECandhasbeendesignedandmanufacturedinaccordancewithSoundEngineeringPractice.KeithShuttleworthftAssociatesLimited2.0INSTALLATIONMounting(FixedVersion)-TheSQ2SanitarySampleCoolermustbesecurelyfixedusingthemountingbracketsinaverticalpositionthatallowsforthesampletobecollectedfromthebottom.Ifnotcorrectlymounted,thecoolermayairlockandresultinincompletecondensation/cooling,withattendanthazards.Mounting(PortableVersion)-ThelegsprovidedwiththeportableSQ2SanitarySampleCoolermustbesecurelyscrewedbyhandintothebaseofthecooler.Thecoolershouldbemountedinaverticalpositionthatallowsforthesampletobecollectedfromthebottom.Thecoolershouldbesituatedonalevelsurface.Ifnotcorrectlymounted,thecoolermayairlockandresultinincompletecondensation/cooling,withattendanthazards.Particularcaremustbetakentoensurethatthepipeworkforthesampleandcoolingwateraresecureandstrainfreeanddonotresultinexcessiveforce(s)whichmaycausethecoolertotoppleover.Samplepipework-Thesampleinletisatthetopandisviaatri-Clamp©sanitaryconnectionandmaybeconnectedtothesteamlWFIsystemusingeitherfixedpipeworkorasuitablypressure&temperatureratedflexiblehose.Anisolationvalveshouldalwaysbeinstalledatthesamplepointinthesteam/watersystem.AtypicalinstallationwillhaveanisolationvalveonthesteamlWFIpipework(withaminimaldeadleg)whichmaybefollowedbyasuitablecontrolvalvepriortothesamplercooler.TheconnectionbetweenthesteamlWFIsystemshouldbemadeinaccordancewiththeclamp/sealsupplier'sinstructions.Thesamplepipeworkwillbecomeveryhotundernormalworkingconditions,andwillcauseburnsiftouched.Werecommend...