中国组织工程研究与临床康复第14卷第3期2010–01–15出版JournalofClinicalRehabilitativeTissueEngineeringResearchJanuary15,2010Vol.14,No.3ISSN1673-8225CN21-1539/RCODEN:ZLKHAH533DepartmentofTumorSurgery,HainanProvincialPeople’sHospital,Haikou570311,HainanProvince,ChinaWangQing-hua,Nurse-in-charge,DepartmentofTumorSurgery,HainanProvincialPeople’sHospital,Haikou570311,HainanProvince,Chinawangqinghua.1974@yahoo.com.cnReceived:2009-11-08Accepted:2009-12-28海南省人民医院肿瘤外科，海南省海口市570311王清华，女，1974年生，主管护师，造口治疗师，护士长。wangqinghua.1974@yahoo.com.cn中图分类号:R318文献标识码:B文章编号:1673-8225(2010)03-00533-04收稿日期：2009-11-08修回日期：2009-12-28(20091230003/GW•A)藻酸盐敷料的临床应用：与传统材料特征的比较王清华，钟文菲，何盟Clinicalapplicationofalginatedressing:AcomparisonwithtraditionalmaterialsWangQing-hua,ZhongWen-fei,HeMenAbstractOBJECTIVE:Toexplorethecharacteristicsandclinicalapplicationofalginatedressingtoprovidebetterbiologicaldressingforclinicalwoundhealing.METHODS:Acomputer-basedonlinesearchofCNKI,Medline,Wanfang,ScienceDirect,andEidatabaseswasperformedforrelatedarticlespublishedbetweenJanuary1960andOctober2009,withthekeywords“alginate,dressing,clinicalapplication”inChineseandEnglish.Studiesregardingcharacteristicsandclinicalapplicationofalginatedressingwereincluded.RepetitiveandMetaanalysiswereexcluded.Inaddition,relatedbooksweremanuallysearched.RESULTS:Atotalof65articleswerecollected,17wereincluded,and48repetitiveorMetaanalyseswereexcluded.Alginateisnaturalpolysaccharidecarbohydrateextractedfromseatangle,andalginatedressingissoftnon-textilefiberrefinedfromseaweed.Itcontains85%naturalalginatefiberand15%sodiumtvlose.Itcanabsorbeffusion,formgelate,andexchangeNa+/Ca2+witheffusion.Alginatedressinghasbeenwidelyusedinbedsoretreatment,analfistulanursing,stomanursing,anddiabeticfootnursing.Comparedwithtraditionaldressing,infectionrateofalginatedressingislowerduetogoodimpermeability,promotionofregionalvesselproliferationandbloodsupply,aswellasmoistandslightlyacidicenvironmentwhichbenefitsneutrophilfunctionenhancesdisinfection.Moreover,itcanbeusedinwoundhealingfollowingabdominalregionoperationandabscessincisiondrainage.CONCLUSION:Alginatedressingprovidesappropriateenvironmentforwoundgrowth,retainsactivematerialsindiffusion,promotesactivematerialrelease,benefitnecrotictissuesolutionandcellproliferationanddifferentiation,aswellasepithelialcellmigration.Moreover,itmaintainshypoxiastateofwound,stimulatesnewlygeneratedcapillarygrowth,andpromotesgranulationtissuegrowth.WangQH,ZhongWF,HeM.Clinicalapplicationofalginatedressing:acomparisonwithtraditionalmaterials.ZhongguoZuzhiGongchengYanjiuyuLinchuangKangfu.2010;14(3):533-536.[http://www.crter.cnhttp://en.zglckf.com]摘要目的：对澡酸盐敷料的特性及临床应用进行探讨，以期为临床创面愈合提供更好的生物敷料。方法：由第一作者应用计算机检索中国期刊全文数据库、Medline数据库、万方数据库、ScienceDirect数据库、Ei数据库1960-01/2009-10期间相关文献，检索词为“澡酸盐，敷料，临床应用，dressing，alginate”，纳入澡酸盐特性及临床应用方面的研究，排除重复及Meta分析类文献。并手工查阅相关书籍。结果：共检索到65篇相关文献，17篇文献符合纳入标准，排除的48篇文献为重复或Meta分析。藻酸盐是由海带中提取的天然多糖碳水化合物，而藻酸盐敷料是从海藻中提炼的柔软无纺织纤维，它含有85%天然藻酸盐纤维，15%的羧甲基纤维素纳。它的主要功能是吸收渗出...
