CRTER沈阳1200邮政信箱110004kf23385083@sina.comwww.zglckf.com中国组织工程研究与临床康复第11卷第1期2007-01-07出版JournalofClinicalRehabilitativeTissueEngineeringResearchJanuary7,2007Vol.11,No.10引言硅橡胶的医用特性发现于1945年,进入20世纪60年代,国外相继出现了不少有关硅橡胶作为人体植入材料和医疗制品应用的报道[1]。20世纪六七十年代,国外已有许多医用硅橡胶制品[2-6]投入了临床应用。据1996-12美国健康工业制造者协会的资料表明,医疗器械市场份额的60%以上来源于生物医学材料和医用植入体[7]。随着人口的老龄化,现代工业、交通和体育事业的发展,人们对于生物医学高分子材料及其制品的需求量日益增大。国内近十几年来,硅橡胶作为生物适应性材料的研究已取得了很大的进展,并且有许多功能化、系列化的医用硅橡胶制品投入了临床应用。预计21世纪初生物医学高分子材料及其制品的发展将成为国民经济的支柱产业。本文主要检索“EI,SCI,CA,ScienceDirect(Elsevier)”等数据库2000-01/2004-12及中国期刊全文数据库、万方数据1995-01/2006-08有关硅橡胶在医学方面应用的文献,分析硅橡胶的生物医学材料特性☆武卫莉1,李佳2BiomedicalcharacteristicsofsiliconrubberAbstractOBJECTIVE:Tocomprehensivelyanalyzetheapplicationvaluesofsiliconrubberinthedesignofartificialorgans,medicalapparatus,facialplasticsurgeryandmedicalreleasesystem.DATASOURCES:Computer-basedonlinesearchofEI,SCI,CA,ScienceDirect(Elsevier)databaseswereundertakenforarticlesabouttheapplicationofsiliconrubberinmedicinepublishedinEnglishbetweenJanuary2000andDecember2004withthekeywordsof“siliconrubber,medicalmaterials”.Meanwhile,wesearchedtheChinesePeriodicalFull-textDatabaseforrelatedChinesearticlespublishedbetweenJanuary1995andAugust2006withthekeywordsof“siliconrubber,artificialorgan,facialplasticsurgery,rubberapparatus”inChinese.STUDYSELECTION:Thedatawerefirstlyselectedtolookupthefulltextofthearticlesmetthecriteria.Inclusivecriteria:①aboutmedicinalsiliconrubber;②aboutmedicinalrubberapparatus,artificialorganandfacialplasticsurgery.Exclusivecriteria:repetitivestudies.DATAEXTRACTION:Totally109relevantarticlesaboutthemedicinalrubbermaterialswerecollected;afterexcludingtherepetitiveorsimilarresearches,19articlesmettherequest.DATASYNTHESIS:①Artificialorgans:researchanddesignoftheartificiallungs,retina,larynx,finger,joint,tympanum,teeth,jaw,windpipe,catheterandbreast.②Plasticandrepairsurgery:repairofcraniumandstudiesintoartificialskin.③Medicinalapparatus:artificialheartandlung,tipofembryoattractor,medicalelectroplate,bio-sensorandsoon.④Carrierwithmedicalrelease:medicalcapsule,releasingprophylacticstickwithimplantingskin,uterusimplantingagent,vaginaringandsoon.⑤Researchandexpectationofmedicinalsiliconrubber:Tooffermoremedicinalapparatusandartificialorgans.CONCLUSION:Medicalsiliconrubbercanbeusedtodesignandproducemorecheapartificialorgansandmedicinalapparatus,andmakemorematerialsbeappliedinclinictosatisfythedemandofmanypatients.WuWL,LiJ.Applicationofsiliconrubberinmedicine.ZhongguoZuzhiGongchengYanjiuyuLinchuangKangfu2007;11(1):145-147(China)[www.zglckf.com/zglckf/ejournal/upfiles/07-1/1k-145(ps).pdf]摘要目的:综合分析硅橡胶在人造器官设计、医疗器械、整容术和在药物缓释体系的应用意义。资料来源:应用计算机检索“EI,SCI,CA,ScienceDirect(Elsevier)”等数据库2000-01/2004-12有关硅橡胶在医学方面应用的文献,检索词“siliconrubber,medicalmaterials”,限定语言种类为English。同时计算机检索中国期刊全文数据库、万方数据1995-01/2006-08有关硅橡胶在医学方面应用的文献,检索词“硅橡胶,人造器官,整容术,橡胶器械”,限定...
