下载后可任意编辑中药土贝母的现代讨论进展【摘要】 目的介绍土贝母讨论的最新进展,预测其应用前景与新的研发方向。方法该文查阅了大量关于土贝母讨论的中外文献资料,从化学成分、药理活性、制剂开发等方面对其进行比较全面地综述。结果与结论土贝母含有多种化学成分,具有多种显着的药理作用,配合现代提取、制剂工艺,可开发为抗癌、抗病毒以及治疗白血病和艾滋病等多种新药。【关键词】 土贝母; 化学成分; 药理活下载后可任意编辑性; 制剂开发; 临床应用 Abstract:ObjectiveIn this review, new progress of Bolbostemma paniculatum was introduced. Its application perspectives and new research directions were forecasted as well. MethodsReferring to a large number of domestic and foreign literatures, the chemical compositions, pharmacological activities and development of 下载后可任意编辑preparations of Bolbostemma paniculatum were reviewed. Results and ConclusionsMany chemical compositions were reported to isolate from Bolbostemma paniculatum, and correspondingly, many significant pharmacological activities have been detected. Companied with modern extraction and preparation technologies, Bolbostemma paniculatum can be developed into some new drugs 下载后可任意编辑for treating cancer, virus, leukemia and AIDS. Key words:Bolbostemma paniculatum; Chemical compositions; Pharmacological activities; Development of preparations; Clinical applications 土贝母 Bolbostemma paniculatumFranquet,别名假贝母、地苦胆、草贝等,为葫芦科土贝母属植物,以下载后可任意编辑鳞茎入药。性味苦,微寒,归肺、脾经,有散结、消肿、解毒之功能。主要分布于河北、河南、山西、山东、甘肃等省。 1 化学成分 1 皂苷类[1~7]皂苷类为土贝母的主要活性成分,含量较大。现已发现的皂苷共 16 种:土贝母皂苷甲;土贝母皂苷乙;土贝母皂苷丙;土贝母皂苷丁;土贝母皂苷戊;土贝母皂苷Ⅵ(6) ;双糖链皂苷:3-O-α-L-吡喃阿拉伯糖(1 →2)-β-D-吡喃葡萄糖-贝萼皂苷元 2-8-O-β-D-吡喃木糖(1 →3)-α-L-吡喃鼠李糖下载后可任意编辑(1 →2)-α-L-吡喃阿拉...