精品文档---下载后可任意编辑黄芪扶正汤抑制 Lewis 肺癌移植瘤生长及其机制的实验讨论的开题报告【摘要】黄芪扶正汤以黄芪、白术、人参为主要配方，常用于中医药治疗疲劳、虚弱和身体虚弱等症状。本讨论旨在评估黄芪扶正汤对 Lewis 肺癌移植瘤生长的影响，并探讨其作用机制。本讨论将 Lewis 肺癌细胞移植入小鼠体内，制成 Lewis 肺癌移植瘤模型。然后，将小鼠分为治疗组和对比组，治疗组给予黄芪扶正汤，对比组给予生理盐水。观察生长瘤的大小并记录并分析肺癌细胞密度、肿瘤生长指数和生存率。此外，还将分析黄芪扶正汤对瘤内的炎性细胞和免疫细胞浸润的影响。本讨论的目的在于确定黄芪扶正汤是否可以作为潜在的治疗肺癌的中药方剂，以及探究其药理作用机制。【关键词】黄芪扶正汤、Lewis 肺癌、移植瘤、炎性细胞、免疫细胞【Abstract】Huangqi Fuzheng Tang, which consists of Radix Astragali, Rhizoma Atractylodis Macrocephalae, and Radix Ginseng, is a traditional Chinese medicine formula commonly used for treating fatigue, weakness, and physical debility. This study aims to evaluate the effects of Huangqi Fuzheng Tang on the growth of Lewis lung carcinoma (LLC) tumors and to explore its underlying mechanisms.LLC cells were implanted into mice to establish the LLC tumor model. Mice were divided into treatment and control groups, with the treatment group receiving Huangqi Fuzheng Tang and the control group receiving saline. Tumor size was measured, and the density of LLC cells, tumor growth index, and survival rate were analyzed. In addition, the effect of Huangqi Fuzheng Tang on inflammatory cells and immune cells infiltrating the tumor was examined.The purpose of this study is to determine whether Huangqi Fuzheng Tang can be a potential Chinese herbal formula for 精品文档---下载后可任意编辑the treatment of lung cancer and to explore its pharmacological mechanisms.【Keywords】 Huangqi Fuzheng Tang, Lewis lung carcinoma, implantation tumor, inflammatory cells, immune cells
