脑与神经疾病杂志2011年第19卷第4期giealpatient：diagnosisandmanagement．NeurosurgFocus，2004，16：E9．[7]OertelM，BoscardinWJ，ObristWD，eta1．Posttraumatievasospasm：theepidemiology，severity，andtimecourseofanunderes-timatedphenomenon：aprospectivestudyperformedin299patients．JNeurosurg．2005，103：812-824．[8]MoroN，KatayamaY，K~imaJ，eta1．Prophylacticmanagementofexcessivenatriuresiswithhydroeortisoneforefficienthypervolemie[9][1O]293therapyaftersubarachnoidhemorrhage．Stroke，2003，34：2807-2811．KojimaJ，KatayamaY，MoroN，eta1．Cerebralsaltwastinginsubarachnoidhemorrhagerats：model，mechanism，andtoo1．LifeSci，2005，76：2361-237O．KinikST，KandemirN，BaykanA，eta1．Fludrocortisonetreatmentinachildwithseverecerebralsaltwasting．PediatrNeurosurg，2001，35：216-219．(201104_o5收稿)短暂性脑缺血发作的DWI异常表现和临床特点的关系金炜陈观保庞洪波谈世东●【摘要】目的探讨磁共振弥散成像(DWI)责任病灶在短暂性脑缺血发作(TIA)诊断与治疗中的价值及相关因素分析。方法124例TIA患者在发病3天内行头颅MRI及DWI检查，根据DWI有无异常，分为两组(DWI正常组及DWI异常组)，并比较这两组的临床资料情况。结果48例患者有DWI异常(38．7％)，76例无异常(61．3％)，发作持续时间较长(≥60min)、发作频繁、有运动障碍、失语、脑卒中或TIA史及糖尿病的TIA患者更易于出现DWI异常。结论在临床诊断的TIA患者中，症状持续时间较长、发作频繁、运动障碍、失语、脑卒中或TIA史及糖尿病是与DWI异常显著相关的因素。【关键词】磁共振弥散成像；短暂性脑缺血发作；脑梗死；临床特点中图分类号：R743．32文献标识码：A文章编号：1006．351x(2011)04-0293-04ThecorrelationbetweendifusionweightedimagingabnormalitiesandclinicalcharacteristicsinpatientswithtransientischemicattackJINWei．CHENGuan—bao，PANGHong—bo，TANShi—d0ng．DepartmentofNeurologytheSecondPeopleHospitalofWuhuCity，Anhui241000，ChinaC0rrespondingauthor：JINWei，Email：jinwei1963110@sina．con．【Abstract】0bjectiveTostudytheclinicalcharacteristicsassociatedwithdiffusionweightedimagingabnor-malitiesinpatientswithtransientischemicattack．MethodsThedataofDW1werecollectedon124consecutivepatientswithTIAwithin3daysofonset，accordingtoDWI，thepatientweredividedintonormalDWIgroupsandabnormalDWIgroupsandclinicalcharacteristicsoftwogroupshavebeencompared．ResultsDWI-detectedabnormalitieswerepresentin48cases(38．7％)，76patientswithoutabnormalities(61．3％)．ProlongedTIAduration(TIAduration≥60minutes)，multipleepisodes，motordeficits，aphasia，historyofeitherstrokeorTIA，diabetesmellituswereobservedmorefrequentlyintheabnormalgroupthaninthenormalgroup．ConclusionsInTIApatiendts，prolongedTIAduration(TIAduration≥60minutes)，multipleepisodes，motordeficits，aphasia，historyofeitherstrokeorTIA．diabetesmellitusarecorrelatedwithdetectinganabnormalitywithDWI．【Keywords】Difusionweitedimaging；Transientischemicattack；Cerebralinfarction；Clinicalcharacteristics短暂性脑缺血发作(Transientischemicattack，TIA)是反复发作的颈动脉和椎基底动脉系统缺血引作者单位：241000安徽，芜湖市第二人民医院神经内科论著●起局灶的神经功能缺损，TIA是历时短暂并经常反复发作的脑局部供血障碍，导致供血区局限性神经功能缺失，24h内即完全恢复。患者就诊时，多数症状已经294消失，常依靠病史作出诊断。TIA头颅CT及磁共振T，T'加权像常无阳性发现。最近研究磁共振弥散成像(diffusion．weightedimaging，DWI)检查TIA比常规平扫或增强更敏感而准确，并有助于发现患者新近缺血性病灶。我们研究在发病后3天内进行常规MRI和DWI检查的124例TIA患者的临床和MRI资料，探讨TIA患者DWI...
