精品文档---下载后可任意编辑高血压对大鼠动脉瘤模型影响及新型弹簧圈栓塞治疗讨论的开题报告摘要：动脉瘤是一种常见的血管病变并发症，而高血压是动脉瘤形成的重要危险因素。本讨论旨在探究高血压对大鼠动脉瘤模型的影响以及新型弹簧圈栓塞治疗的有效性。采纳自制弹簧圈栓塞装置对大鼠进行动脉瘤模型制备，并运用药理学、病理学、生化学等方法观察高血压和栓塞治疗对大鼠动脉瘤形成、生长和凋亡的影响。估计本讨论的结果将有助于深化了解高血压与动脉瘤形成的关系，以及探究新型治疗方案的可行性。关键词：高血压；动脉瘤；弹簧圈栓塞治疗；大鼠；生物学效应Abstract: Arterial aneurysm is a common complication of vascular disease, and hypertension is an important risk factor for aneurysm formation. This study aims to explore the effects of hypertension on rat arterial aneurysm models and the effectiveness of a novel spring coil embolization therapy. A homemade spring coil embolization device was used to prepare arterial aneurysm models in rats, and pharmacological, pathological, and biochemical methods were used to observe the effects of hypertension and embolization therapy on the formation, growth, and apoptosis of rat arterial aneurysms. The results of this study are expected to help better understand the relationship between hypertension and aneurysm formation, and explore the feasibility of a novel treatment approach.Keywords: hypertension; arterial aneurysm; spring coil embolization therapy; rat; biological effects.
